Across TCGA pan-cancer cohorts, RNU6ATAC15P RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of RNU6ATAC15P’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where RNU6ATAC15P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6ATAC15P is over-expressed in tumor.
LUSC are the cancer types where RNU6ATAC15P tumor–normal differential expression is most reproducible.