RNU6ATAC14P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6ATAC14P RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of RNU6ATAC14P’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where RNU6ATAC14P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6ATAC14P is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

BRCA, KICH, and KIRC are the cancer types where RNU6ATAC14P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6ATAC14P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
BRCAAllIII,IV+1.093<.0018view →
KICHMaleAll−0.837<.0016view →
KIRCMaleAll+0.275.0263view →
UCECAllAll−0.296.0362view →
LUADAllAll+0.136.0272view →
PRADAllAll−0.113.0462view →
LUSCFemaleAll+0.265.0391view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

RNU6ATAC14P–BRCA

Tumor-vs-normal expression box plot for RNU6ATAC14P RNA in BRCA.

Open the BRCA breakdown →

Exploration