RNU6-998P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-998P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-998P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-998P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-998P expression acts as an unfavorable survival marker, although some lineages such as LIHC and LUAD show a favorable association.

TGCT, CHOL, and KICH are the cancer types where RNU6-998P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
TGCTOSTertileIII,IV0.0031.000<.00154view →
CHOLDFSTertileII,III,IV0.0940.446.00736view →
KICHDFSTertileII,III,IV0.3480.916.00130view →
THCADFSTertileIV0.5720.874.01624view →
GBMDFSTertileAll0.1430.314.02618view →
ACCOSTertileIII,IV0.1890.757<.00118view →
LIHCOSTertileII,III,IV1.0000.710.01515view →
COADDFSTertileIV0.1980.500.0339view →
MESODFSTertileIII,IV0.2390.438.0379view →
SKCMDFSTertileIV0.0160.541.0089view →
PCPGOSTertileAll0.9251.000.0179view →
LUADDFSTertileIII,IV0.8100.546.0306view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-998P–TGCT (OS)

Kaplan–Meier survival curve for RNU6-998P RNA-high vs -low samples in TGCT.

Open the TGCT breakdown →

Exploration