RNU6-994P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-994P RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated RNU6-994P data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RNU6-994P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-994P expression acts as an unfavorable survival marker.

COAD, ACC, and ESCA are the cancer types where RNU6-994P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADOSTertileIV0.0390.660<.00154view →
ACCDFSTertileII,III,IV0.2690.670<.00154view →
ESCAOSTertileIV0.0950.512.00836view →
OVOSTertileIV0.0280.759.00236view →
UCSDFSTertileIV0.1320.718.00236view →
SKCMDFSTertileAll0.0660.209.00424view →
SARCOSTertileAll0.0320.861<.00124view →
KIRCDFSTertileIV0.1270.630.03918view →
LGGDFSTertileAll0.7380.849.0055view →
Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

Exploration