RNU6-990P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-990P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-990P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-990P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-990P expression acts as an unfavorable survival marker.

HNSC, STAD, and OV are the cancer types where RNU6-990P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileII,III,IV0.0290.712<.00181view →
STADDFSTertileIV0.0830.379.00145view →
OVOSTertileIV0.0760.759.01436view →
BRCADFSTertileAll0.7770.903.03330view →
KIRCOSTertileAll0.3770.633.02424view →
PRADOSTertileAll0.8160.990<.00118view →
UCECDFSTertileIV0.2060.704.03318view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

Exploration