RNU6-98P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-98P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-98P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-98P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-98P expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UVM, KICH, and DLBC are the cancer types where RNU6-98P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMDFSTertileAll0.0320.762<.00190view →
KICHOSTertileAll0.1610.881<.00172view →
DLBCDFSTertileII,III,IV0.0650.829<.00154view →
ESCAOSTertileII,III,IV0.2960.570<.00152view →
BLCAOSTertileAll0.4840.713.01536view →
TGCTOSTertileAll0.0830.969<.00136view →
COADOSTertileIII,IV0.3980.787.00136view →
LIHCOSTertileII,III,IV0.0930.696<.00127view →
STADDFSTertileIV0.1070.565.00418view →
KIRCOSTertileAll0.2740.635.00418view →
SARCOSTertileAll0.0320.861<.00118view →
BRCADFSTertileAll0.3590.529.03112view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration