RNU6-988P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-988P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-988P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-988P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-988P expression acts as an unfavorable survival marker, although some lineages such as BLCA and CESC show a favorable association.

MESO, LIHC, and BLCA are the cancer types where RNU6-988P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
MESOOSTertileIV0.1370.669<.00157view →
LIHCDFSTertileAll0.2160.581<.00142view →
BLCADFSTertileIV0.7430.278.01627view →
SKCMDFSTertileIV0.0360.433<.00127view →
CESCOSTertileAll0.8820.757.00926view →
KIRCDFSQuartileIV0.3590.535.02114view →
ESCAOSMedianIII,IV0.6290.307.00412view →
STADDFSMedianIII,IV0.6590.489.0208view →
OVDFSQuartileIV0.3140.499.0366view →
KIRPDFSTertileAll1.0000.898.0203view →
LAMLDFSMedianAll0.6890.470.0442view →
LUADOSQuartileII,III,IV0.6320.775.0451view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-988P–MESO (OS)

Kaplan–Meier survival curve for RNU6-988P RNA-high vs -low samples in MESO.

Open the MESO breakdown →

Exploration