RNU6-986P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-986P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-986P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-986P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-986P expression acts as an unfavorable survival marker, although some lineages such as LUAD and LAML show a favorable association.

THCA, ACC, and BLCA are the cancer types where RNU6-986P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
THCAOSTertileII,III,IV0.5170.853<.001117view →
ACCOSTertileIII,IV0.1670.798<.00157view →
BLCAOSTertileIV0.2060.492.01048view →
SKCMOSTertileIV0.1790.755<.00118view →
LUADDFSTertileAll0.6860.327.01518view →
LAMLDFSTertileAll0.6260.265.01012view →
MESODFSTertileAll0.2180.378.0439view →
PAADOSTertileII,III,IV0.3360.572.0159view →
ESCAOSTertileIII,IV0.6040.332.0319view →
LIHCDFSTertileAll0.1220.555.0099view →
READDFSTertileIV0.0950.697.0149view →
LGGOSTertileAll0.3350.472.0293view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration