RNU6-957P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-957P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-957P data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher RNU6-957P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-957P expression acts as an unfavorable survival marker, although some lineages such as STAD and COAD show a favorable association.

UCS, KIRP, and KIRC are the cancer types where RNU6-957P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCSDFSTertileAll0.0680.533<.00154view →
KIRPDFSTertileII,III,IV0.1910.781<.00148view →
KIRCDFSTertileIV0.2060.503.01936view →
STADOSMedianIV0.7050.159.01128view →
BRCADFSTertileAll0.3500.546.00218view →
SKCMOSTertileIII,IV0.2320.705.02418view →
SARCOSTertileAll0.1300.866<.00118view →
COADDFSTertileAll1.0000.678.02115view →
ESCAOSMedianAll0.4140.567.01712view →
LUSCDFSTertileAll0.6430.795.0253view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration