RNU6-953P

Across TCGA pan-cancer cohorts, RNU6-953P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-953P data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher RNU6-953P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-953P expression acts as an unfavorable survival marker, although some lineages such as ESCA show a favorable association.

LUAD, HNSC, and UCEC are the cancer types where RNU6-953P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	All	0.079	0.788	<.001	54	view →
HNSC	DFS	Tertile	All	0.375	0.698	.018	36	view →
UCEC	DFS	Tertile	All	0.116	0.651	<.001	36	view →
THCA	OS	Tertile	All	0.585	0.929	<.001	27	view →
LIHC	DFS	Tertile	III,IV	0.137	0.362	.003	27	view →
TGCT	OS	Tertile	All	0.542	0.969	<.001	18	view →
READ	DFS	Tertile	II,III,IV	0.255	0.816	.015	18	view →
SKCM	DFS	Tertile	All	0.433	0.760	.032	15	view →
LGG	DFS	Tertile	All	0.251	0.449	.021	15	view →
ESCA	OS	Quartile	III,IV	0.809	0.363	.021	14	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-953P–LUAD (OS)

Open the LUAD breakdown →