RNU6-94P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-94P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNU6-94P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-94P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-94P expression acts as an unfavorable survival marker, although some lineages such as SKCM and THYM show a favorable association.

KIRC, SKCM, and THYM are the cancer types where RNU6-94P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSTertileAll0.5090.686<.00182view →
SKCMOSMedianAll0.4080.263<.00139view →
THYMOSMedianAll1.0000.702<.00135view →
BLCADFSMedianAll0.3880.275.01130view →
PAADDFSMedianAll0.3540.211.01520view →
STADDFSQuartileAll0.3490.592.02119view →
PRADDFSMedianAll0.6830.893<.00118view →
THCADFSMedianAll0.9770.906<.00114view →
UVMDFSTertileIII,IV0.2700.791.01413view →
KICHOSMedianIII,IV0.7851.000.0159view →
LUADOSTertileIII,IV0.5630.205.0129view →
KIRPDFSQuartileAll0.9540.835.0167view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RNU6-94P–KIRC (OS)

Kaplan–Meier survival curve for RNU6-94P RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration