RNU6-942P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-942P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-942P’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where RNU6-942P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-942P is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

THCA, KIRP, and BRCA are the cancer types where RNU6-942P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-942P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
THCAAllIII,IV−0.334.0075view →
KIRPMaleIII,IV+0.474.0123view →
BRCAFemaleAll+0.314.0102view →
KICHAllII,III,IV+0.101.0341view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration