RNU6-925P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-925P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNU6-925P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-925P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-925P expression acts as an unfavorable survival marker, although some lineages such as BLCA and BRCA show a favorable association.

BLCA, BRCA, and COAD are the cancer types where RNU6-925P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCADFSMedianIII,IV0.4990.229<.00183view →
BRCAOSTertileAll0.9740.931.00363view →
COADDFSMedianIII,IV0.5850.741.00338view →
GBMDFSQuartileAll0.4620.146.00128view →
THCADFSQuartileII,III,IV0.7841.000<.00124view →
ACCDFSMedianAll0.4510.701.01016view →
UCECOSTertileAll0.8340.900.02816view →
LUSCOSTertileAll0.7890.692.00614view →
LUADOSMedianIV0.7110.286.01912view →
UVMOSMedianIII,IV0.2961.000.00512view →
LAMLDFSMedianAll0.6060.338.00510view →
CHOLOSMedianAll0.8630.404.0289view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RNU6-925P–BLCA (DFS)

Kaplan–Meier survival curve for RNU6-925P RNA-high vs -low samples in BLCA.

Open the BLCA breakdown →

Exploration