RNU6-91P

Across TCGA pan-cancer cohorts, RNU6-91P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-91P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-91P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-91P expression acts as an unfavorable survival marker, although some lineages such as KIRC and OV show a favorable association.

CHOL, MESO, and PAAD are the cancer types where RNU6-91P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	DFS	Tertile	II,III,IV	0.030	0.430	<.001	99	view →
MESO	OS	Tertile	IV	0.077	0.592	.019	45	view →
PAAD	DFS	Tertile	All	0.260	0.496	<.001	27	view →
KIRC	DFS	Tertile	III,IV	0.930	0.671	.008	26	view →
UCS	OS	Tertile	All	0.202	0.583	.043	18	view →
TGCT	OS	Tertile	II,III,IV	0.752	1.000	.019	18	view →
SARC	OS	Tertile	All	0.181	0.610	<.001	18	view →
STAD	DFS	Tertile	IV	0.096	0.428	.002	17	view →
OV	DFS	Median	III,IV	0.411	0.329	.006	12	view →
SKCM	OS	Tertile	IV	0.415	0.861	.014	9	view →
COAD	OS	Tertile	III,IV	0.172	0.698	.023	9	view →
UVM	DFS	Tertile	All	0.464	0.758	.043	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-91P–CHOL (DFS)

Open the CHOL breakdown →