RNU6-915P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-915P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-915P data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher RNU6-915P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-915P expression acts as an unfavorable survival marker, although some lineages such as KIRP and ESCA show a favorable association.

COAD, MESO, and THCA are the cancer types where RNU6-915P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
COADDFSTertileIII,IV0.3870.623.00189view →
MESOOSTertileIV0.3360.667.00563view →
THCADFSQuartileII,III,IV0.2380.941.00243view →
UCECDFSTertileAll0.8160.906.00130view →
PCPGOSTertileAll0.8740.992<.00127view →
ACCOSTertileIII,IV0.1890.764.0049view →
LGGDFSQuartileAll0.2400.503.0069view →
SKCMDFSTertileII,III,IV0.4630.586.0389view →
READDFSTertileIV0.3410.685.0439view →
KIRPOSTertileAll0.9720.913.0377view →
PRADOSQuartileAll0.6220.935.0076view →
ESCADFSMedianAll0.5750.430.0324view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration