Across TCGA pan-cancer cohorts, RNU6-899P RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated RNU6-899P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-899P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-899P expression acts as an unfavorable survival marker, although some lineages such as STAD and DLBC show a favorable association.

ACC, STAD, and LIHC are the cancer types where RNU6-899P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.153	0.641	.002	57	view →
STAD	DFS	Tertile	III,IV	0.723	0.538	.005	56	view →
LIHC	DFS	Tertile	All	0.076	0.535	<.001	36	view →
CESC	DFS	Tertile	II,III,IV	0.573	0.809	.003	36	view →
LGG	OS	Tertile	All	0.462	0.818	<.001	27	view →
THYM	DFS	Tertile	II,III,IV	0.227	0.800	.004	18	view →
LAML	DFS	Tertile	All	0.213	0.595	.038	18	view →
PCPG	OS	Tertile	All	0.526	0.975	<.001	18	view →
KIRC	DFS	Tertile	III,IV	0.266	0.500	.024	15	view →
THCA	OS	Tertile	III,IV	0.585	0.888	.002	12	view →
SARC	DFS	Tertile	All	0.162	0.638	.002	9	view →
SKCM	DFS	Tertile	III,IV	0.076	0.269	.022	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

Exploration

Same gene, other analysis: RNU6-899P tumor-vs-normal RNA expression · all RNU6-899P data types