RNU6-881P

Across TCGA pan-cancer cohorts, RNU6-881P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-881P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-881P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-881P expression acts as an unfavorable survival marker, although some lineages such as ESCA and LAML show a favorable association.

BLCA, SKCM, and PAAD are the cancer types where RNU6-881P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.185	0.621	<.001	90	view →
SKCM	OS	Tertile	All	0.374	0.792	<.001	81	view →
PAAD	DFS	Tertile	All	0.118	0.468	.012	45	view →
OV	DFS	Tertile	IV	0.147	0.469	.011	36	view →
THCA	OS	Tertile	II,III,IV	0.189	0.877	.005	36	view →
ESCA	OS	Tertile	III,IV	1.000	0.376	.021	18	view →
ACC	DFS	Tertile	All	0.195	0.748	.003	9	view →
LAML	DFS	Median	All	0.734	0.394	<.001	8	view →
STAD	OS	Tertile	All	0.816	0.639	.023	6	view →
KIRP	OS	Tertile	All	0.749	0.909	.043	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-881P–BLCA (OS)

Open the BLCA breakdown →