RNU6-880P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-880P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU6-880P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-880P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-880P expression acts as an unfavorable survival marker, although some lineages such as ESCA and HNSC show a favorable association.

KICH, KIRP, and READ are the cancer types where RNU6-880P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KICHOSTertileIII,IV0.1620.808.00169view →
KIRPOSTertileAll0.4910.767.00158view →
READDFSTertileIV0.3260.712.00557view →
STADOSMedianIII,IV0.3750.594.00455view →
BLCAOSQuartileIV0.3030.648.00337view →
ACCDFSTertileAll0.3350.706.00236view →
KIRCDFSQuartileII,III,IV0.2890.586.00432view →
SKCMDFSTertileIV0.0380.477<.00124view →
ESCADFSTertileAll1.0000.504.02321view →
LIHCOSTertileIII,IV0.0650.761<.00118view →
HNSCOSQuartileIV0.7630.602.0307view →
CESCDFSMedianIV0.3040.678.0286view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration