RNU6-879P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-879P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU6-879P data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher RNU6-879P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-879P expression acts as an unfavorable survival marker, although some lineages such as OV and KIRP show a favorable association.

SKCM, ACC, and UVM are the cancer types where RNU6-879P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
SKCMOSTertileAll0.4830.808<.00181view →
ACCOSTertileIII,IV0.1670.798<.00172view →
UVMOSTertileAll0.0370.835<.00154view →
LIHCOSTertileII,III,IV0.4310.724.00145view →
HNSCOSTertileAll0.2410.606.02245view →
UCSDFSTertileIII,IV0.1450.462.00236view →
COADDFSTertileIV0.2110.509.00727view →
CHOLDFSTertileAll0.0800.459.01727view →
THYMOSTertileII,III,IV0.0680.970<.00121view →
LUSCDFSTertileIII,IV0.0790.751.02418view →
KICHOSTertileIII,IV0.1780.847<.00118view →
TGCTOSTertileII,III,IV0.6701.000.00518view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration