RNU6-875P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-875P RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated RNU6-875P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-875P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-875P expression acts as an unfavorable survival marker, although some lineages such as SKCM and STAD show a favorable association.

ACC, UCEC, and THYM are the cancer types where RNU6-875P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSTertileAll0.5950.875<.001165view →
UCECDFSTertileAll0.5030.677<.00138view →
THYMOSTertileIII,IV0.6101.000.01033view →
KICHOSTertileAll0.4200.936.00130view →
CESCDFSTertileAll0.3630.651.00924view →
KIRCDFSTertileAll0.5200.659.00724view →
DLBCDFSTertileIII,IV0.1370.761.01419view →
LUSCDFSQuartileIII,IV0.1560.840.00119view →
THCAOSTertileII,III,IV0.8920.983.00116view →
READDFSTertileIV0.3480.717.00115view →
LIHCDFSQuartileII,III,IV0.2660.463.02213view →
SKCMOSTertileAll0.4180.295.01612view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

RNU6-875P–ACC (OS)

Kaplan–Meier survival curve for RNU6-875P RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration