RNU6-85P

Across TCGA pan-cancer cohorts, RNU6-85P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-85P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-85P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-85P expression acts as an unfavorable survival marker, although some lineages such as ESCA and STAD show a favorable association.

MESO, KIRC, and PCPG are the cancer types where RNU6-85P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Tertile	III,IV	0.082	0.414	.007	54	view →
KIRC	DFS	Tertile	IV	0.167	0.605	<.001	36	view →
PCPG	OS	Tertile	All	0.142	0.963	<.001	27	view →
BRCA	OS	Tertile	All	0.270	0.589	.006	24	view →
UCEC	DFS	Tertile	All	0.146	0.651	.016	24	view →
ESCA	DFS	Median	All	0.440	0.232	.006	21	view →
STAD	OS	Tertile	III,IV	0.670	0.411	.025	18	view →
HNSC	DFS	Tertile	III,IV	0.162	0.682	<.001	18	view →
GBM	DFS	Tertile	All	0.071	0.288	.009	18	view →
PRAD	OS	Tertile	All	0.944	0.995	.001	18	view →
KIRP	OS	Tertile	All	0.756	0.952	.002	12	view →
PAAD	OS	Tertile	II,III,IV	0.210	0.556	.007	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

RNU6-85P–MESO (DFS)

Open the MESO breakdown →