Across TCGA pan-cancer cohorts, RNU6-839P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU6-839P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-839P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-839P expression acts as an unfavorable survival marker, although some lineages such as KIRC show a favorable association.

BRCA, KIRC, and SKCM are the cancer types where RNU6-839P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.667	0.963	.008	24	view →
KIRC	DFS	Tertile	All	0.956	0.864	.018	15	view →
SKCM	DFS	Tertile	All	0.046	0.728	<.001	9	view →
CESC	DFS	Tertile	All	0.169	0.553	.031	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-839P tumor-vs-normal RNA expression · all RNU6-839P data types