RNU6-822P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-822P RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated RNU6-822P data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher RNU6-822P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-822P expression acts as an unfavorable survival marker, although some lineages such as PAAD and SKCM show a favorable association.

CHOL, THCA, and UCEC are the cancer types where RNU6-822P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CHOLDFSTertileAll0.0300.500<.001135view →
THCAOSTertileAll0.7770.943<.00199view →
UCECDFSTertileAll0.2400.662.00184view →
COADOSTertileAll0.2130.628.00169view →
STADDFSTertileAll0.2550.548<.00136view →
KICHDFSTertileAll0.1620.862.01430view →
ACCDFSTertileAll0.1870.604.01618view →
HNSCDFSTertileAll0.3710.666.00918view →
PAADDFSTertileII,III,IV0.7140.338.03018view →
ESCAOSTertileAll0.4660.712.00718view →
SKCMDFSTertileIII,IV0.7610.458.02712view →
LIHCOSTertileII,III,IV0.4240.699.0449view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

Exploration