RNU6-79P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-79P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-79P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-79P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-79P expression acts as an unfavorable survival marker, although some lineages such as LAML and PAAD show a favorable association.

KIRC, UVM, and LIHC are the cancer types where RNU6-79P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSTertileAll0.4850.660<.00190view →
UVMOSTertileAll0.5180.835<.00187view →
LIHCDFSTertileAll0.1510.564<.00172view →
LAMLDFSQuartileAll0.5050.228<.00144view →
SKCMOSTertileIII,IV0.4200.720.00136view →
BLCADFSTertileAll0.3170.530.02827view →
PAADDFSTertileAll0.7650.264.02318view →
MESOOSTertileAll0.2860.568.01418view →
OVOSTertileII,III,IV0.8710.829.01618view →
READOSTertileAll0.1560.692.01018view →
SARCOSTertileAll0.4920.837<.00112view →
PCPGDFSTertileAll0.6940.928.0339view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration