RNU6-789P

Across TCGA pan-cancer cohorts, RNU6-789P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-789P data layer.

The strongest signal is observed in mesothelioma (MESO), where higher RNU6-789P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-789P expression acts as an unfavorable survival marker, although some lineages such as BLCA and GBM show a favorable association.

MESO, KICH, and BLCA are the cancer types where RNU6-789P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	IV	0.175	0.485	.003	93	view →
KICH	OS	Tertile	III,IV	0.178	0.847	<.001	60	view →
BLCA	OS	Tertile	II,III,IV	0.788	0.586	.008	57	view →
UVM	OS	Tertile	III,IV	0.037	0.815	<.001	42	view →
READ	OS	Tertile	IV	0.111	0.893	<.001	27	view →
GBM	DFS	Tertile	All	0.413	0.178	.030	21	view →
COAD	OS	Tertile	IV	0.092	0.676	<.001	18	view →
SKCM	DFS	Tertile	IV	0.035	0.476	.002	18	view →
HNSC	OS	Tertile	IV	1.000	0.599	.021	15	view →
LAML	DFS	Median	All	0.590	0.299	.002	8	view →
STAD	OS	Median	All	0.730	0.597	.009	7	view →
ESCA	OS	Tertile	III,IV	0.617	0.340	.026	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-789P–MESO (DFS)

Open the MESO breakdown →