RNU6-786P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-786P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNU6-786P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-786P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-786P expression acts as an unfavorable survival marker, although some lineages such as BLCA and COAD show a favorable association.

UVM, CHOL, and UCS are the cancer types where RNU6-786P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileAll0.1360.919<.00190view →
CHOLOSTertileIII,IV0.0240.772.00872view →
UCSOSTertileAll0.2550.703.00272view →
UCECDFSTertileIV0.2950.736.00854view →
LUSCDFSTertileII,III,IV0.2260.403.01248view →
MESODFSTertileAll0.1240.483.01627view →
BLCADFSTertileIV1.0000.279.00718view →
SKCMDFSTertileIV0.0360.433<.0019view →
COADDFSTertileAll0.7720.513.0379view →
PCPGDFSTertileAll0.3280.885.0019view →
STADDFSQuartileAll0.2760.422.0298view →
BRCAOSTertileIV0.2740.647.0396view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RNU6-786P–UVM (OS)

Kaplan–Meier survival curve for RNU6-786P RNA-high vs -low samples in UVM.

Open the UVM breakdown →

Exploration