RNU6-781P

Across TCGA pan-cancer cohorts, RNU6-781P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-781P data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher RNU6-781P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-781P expression acts as an unfavorable survival marker, although some lineages such as SKCM show a favorable association.

KICH, READ, and UVM are the cancer types where RNU6-781P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
READ	DFS	Tertile	All	0.270	0.713	<.001	54	view →
UVM	OS	Tertile	All	0.136	0.919	<.001	51	view →
ACC	OS	Tertile	II,III,IV	0.135	0.658	.010	39	view →
LUSC	DFS	Tertile	All	0.169	0.521	.001	30	view →
OV	DFS	Tertile	IV	0.250	0.490	.024	18	view →
THCA	OS	Tertile	All	0.980	0.981	.011	18	view →
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	18	view →
LIHC	DFS	Tertile	All	0.311	0.548	.030	18	view →
LAML	DFS	Tertile	All	0.188	0.602	.011	18	view →
SKCM	OS	Tertile	III,IV	0.891	0.352	.022	15	view →
COAD	DFS	Tertile	IV	0.035	0.501	<.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

RNU6-781P–KICH (DFS)

Open the KICH breakdown →