RNU6-77P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-77P RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated RNU6-77P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-77P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-77P expression acts as an unfavorable survival marker.

KIRC, LIHC, and ESCA are the cancer types where RNU6-77P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileIII,IV0.1580.477.01066view →
LIHCOSTertileII,III,IV0.5230.741.00763view →
ESCAOSTertileIV0.0950.512.00836view →
LUADDFSTertileIV0.3420.893<.00136view →
COADOSTertileIII,IV0.1630.791.00427view →
SARCOSTertileAll0.0200.828<.00121view →
READDFSTertileAll0.0840.845<.00118view →
HNSCDFSTertileAll0.4730.715.0369view →
MESOOSTertileAll0.1690.556.0439view →
LUSCOSTertileAll0.2330.526.0216view →
TGCTOSTertileAll0.9381.000.0446view →
SKCMDFSTertileIII,IV0.0910.270.0326view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

Exploration