RNU6-777P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-777P RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated RNU6-777P data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher RNU6-777P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-777P expression acts as an unfavorable survival marker, although some lineages such as MESO show a favorable association.

ACC, KIRC, and TGCT are the cancer types where RNU6-777P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSTertileAll0.1850.811<.00190view →
KIRCOSTertileAll0.5040.654.00260view →
TGCTOSTertileIII,IV0.0031.000<.00160view →
PAADDFSTertileAll0.2110.488.01545view →
SKCMOSTertileIII,IV0.3760.820.00239view →
OVOSTertileIV0.0830.759.02736view →
STADOSTertileII,III,IV0.3480.601.00736view →
LGGOSTertileAll0.1580.450.00530view →
SARCOSTertileAll0.1640.747<.00127view →
MESODFSTertileAll0.5630.173.02521view →
THYMDFSTertileAll0.1390.824.01118view →
LIHCOSTertileII,III,IV0.4040.700.03318view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

Exploration