RNU6-765P

Across TCGA patient cohorts, RNU6-765P RNA expression is significantly associated with the go_rna of many other GO terms, with 5,824 significant associations in total. STAD shows the largest number of these associations.

The most reproducible RNU6-765P-associated GO terms across cancer lineages are Extrinsic apoptotic signaling pathway via death domain receptors, Organelle membrane fusion, and Regulation of superoxide metabolic process. Each is linked with RNU6-765P in more than 4 cancer types. Because this analysis shows association rather than direction, both RNU6-765P-to-partner and partner-to-RNU6-765P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Extrinsic apoptotic signaling pathway via death domain receptors grouped by RNU6-765P-low versus RNU6-765P-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-765P→partner) and Y-score (partner→RNU6-765P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Extrinsic apoptotic signaling pathway via death domain receptors →	+0.205	+0.176	<.001	<.001	3	4
ESCA	Organelle membrane fusion →	+0.178	+0.138	<.001	.001	3	4
ESCA	Regulation of superoxide metabolic process →	+0.162	+0.157	<.001	.001	3	4
ESCA	Positive regulation of peptidase activity →	+0.172	+0.149	<.001	.003	2	5
ESCA	Response to gamma radiation →	+0.211	+0.104	<.001	.006	3	4
ESCA	Regulation of peptidyl-threonine phosphorylation →	+0.142	+0.085	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,824 associations by consensus.

Extrinsic apoptotic signaling pathway via death domain receptors by RNU6-765P expression — ESCA

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