RNU6-760P

Across TCGA pan-cancer cohorts, RNU6-760P RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of RNU6-760P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where RNU6-760P RNA is repressed in tumor relative to normal tissue. In most cancer types RNU6-760P is over-expressed in tumor, although a few such as KIRP and LUSC show the opposite, repressed pattern.

KIRP, LUSC, and KICH are the cancer types where RNU6-760P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-760P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	II,III,IV	−0.275	.003	6	view →
LUSC	Male	All	−0.238	.026	3	view →
KICH	Male	III,IV	+0.390	.028	2	view →
LUAD	Female	II,III,IV	−0.298	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

RNU6-760P–KIRP

Open the KIRP breakdown →