RNU6-759P

Across TCGA pan-cancer cohorts, RNU6-759P RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of RNU6-759P’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where RNU6-759P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types RNU6-759P is over-expressed in tumor, although a few such as LUAD and BRCA show the opposite, repressed pattern.

KIRC, CHOL, and KIRP are the cancer types where RNU6-759P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in RNU6-759P RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.236	.002	7	view →
CHOL	All	All	+0.835	<.001	5	view →
KIRP	All	IV	+0.900	.003	4	view →
BLCA	All	All	+0.514	.025	4	view →
LUAD	Female	II,III,IV	−0.510	.003	3	view →
UCEC	All	III,IV	+0.718	.039	2	view →
STAD	All	All	+0.536	.021	2	view →
BRCA	All	III,IV	−0.375	.026	2	view →
COAD	All	All	+0.263	.010	2	view →
KICH	Female	III,IV	+0.553	.009	1	view →
HNSC	All	III,IV	+0.293	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

RNU6-759P–KIRC

Open the KIRC breakdown →