RNU6-754P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-754P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-754P data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher RNU6-754P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-754P expression acts as an unfavorable survival marker.

PAAD, SKCM, and HNSC are the cancer types where RNU6-754P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
PAADDFSTertileAll0.0680.484<.00172view →
SKCMOSTertileII,III,IV0.2330.735.01539view →
HNSCDFSTertileAll0.2090.710.03236view →
ESCAOSTertileAll0.1980.872.00336view →
STADDFSTertileIV0.0830.379.00127view →
LIHCOSTertileAll0.2580.690.02418view →
KIRPOSTertileAll0.5990.903.0179view →
LGGDFSTertileAll0.1340.402.0456view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration