Across TCGA pan-cancer cohorts, RNU6-753P RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated RNU6-753P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-753P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-753P expression acts as an unfavorable survival marker, although some lineages such as STAD show a favorable association.

BRCA, KIRC, and STAD are the cancer types where RNU6-753P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	II,III,IV	0.133	0.567	<.001	72	view →
KIRC	DFS	Tertile	IV	0.167	0.605	<.001	36	view →
STAD	DFS	Tertile	III,IV	0.769	0.312	.048	6	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: RNU6-753P tumor-vs-normal RNA expression · all RNU6-753P data types