RNU6-749P

Across TCGA patient cohorts, RNU6-749P RNA expression is significantly associated with the mutation status of many other genes, with 39 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible RNU6-749P-associated genes across cancer lineages are PACSIN2, PAPLN, and NDRG1. Each is linked with RNU6-749P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-749P-to-partner and partner-to-RNU6-749P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PACSIN2 grouped by RNU6-749P-low versus RNU6-749P-high in BRCA.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-749P→partner) and Y-score (partner→RNU6-749P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PACSIN2 →	+7.057	+0.121	.009	<.001	3	1
BRCA	PAPLN →	+7.473	+0.151	.007	<.001	3	1
BRCA	NDRG1 →	+8.057	+0.202	.005	<.001	3	1
BRCA	GTPBP4 →	+8.057	+0.199	.005	<.001	3	1
BRCA	SLC10A3 →	+9.057	+0.299	.003	<.001	3	1
BRCA	TAOK3 →	+7.473	+0.149	.007	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

PACSIN2 by RNU6-749P expression — BRCA

Explore this box plot interactively →