RNU6-748P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-748P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-748P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-748P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-748P expression acts as an unfavorable survival marker, although some lineages such as BRCA show a favorable association.

KIRC, KICH, and UVM are the cancer types where RNU6-748P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSMedianIV0.3480.608.00339view →
KICHDFSQuartileII,III,IV0.2620.866<.00128view →
UVMOSTertileIII,IV0.1360.874<.00118view →
PCPGOSTertileAll0.7820.958.01515view →
ACCDFSTertileIII,IV0.1730.496.0489view →
GBMOSTertileAll0.2940.431.0389view →
READOSTertileIV0.0771.000.0149view →
CESCDFSTertileIII,IV0.2040.622.0266view →
BRCADFSQuartileIII,IV0.9620.839.0176view →
COADDFSTertileII,III,IV0.2580.532.0193view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-748P–KIRC (DFS)

Kaplan–Meier survival curve for RNU6-748P RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration