RNU6-746P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-746P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-746P data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher RNU6-746P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-746P expression acts as an unfavorable survival marker.

HNSC, UVM, and STAD are the cancer types where RNU6-746P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileAll0.1560.751<.001144view →
UVMOSTertileII,III,IV0.2180.718.00672view →
STADOSTertileAll0.2600.589.03118view →
LUSCOSTertileAll0.2880.728.01018view →
LAMLDFSTertileAll0.1400.572.04018view →
KIRCDFSTertileAll0.1270.865<.00118view →
SKCMDFSTertileIII,IV0.0580.648.0019view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

Exploration