RNU6-727P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-727P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-727P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-727P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-727P expression acts as an unfavorable survival marker.

UVM, BLCA, and UCEC are the cancer types where RNU6-727P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileAll0.0750.859<.001108view →
BLCAOSTertileIII,IV0.2280.660<.00190view →
UCECOSTertileII,III,IV0.1700.771<.00190view →
PAADOSTertileAll0.1000.590<.00136view →
KIRCDFSTertileIV0.1270.630.03930view →
THCADFSTertileIV0.1260.805.00227view →
SKCMDFSTertileII,III,IV0.2330.685.01518view →
LUSCOSTertileII,III,IV0.2500.778.00718view →
KIRPOSTertileAll0.1110.702.00118view →
CESCDFSTertileAll0.1780.551.01612view →
Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

Exploration