RNU6-725P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-725P RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated RNU6-725P data layer.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher RNU6-725P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-725P expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

OV, COAD, and READ are the cancer types where RNU6-725P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
OVOSTertileAll0.5400.711<.001108view →
COADOSTertileII,III,IV0.2320.793<.001102view →
READOSTertileAll0.1660.830<.00172view →
DLBCOSTertileII,III,IV0.1150.839<.00163view →
MESOOSTertileAll0.0520.528.01654view →
ACCOSTertileAll0.1330.686.00454view →
LGGOSTertileAll0.5120.822<.00139view →
GBMDFSTertileAll0.1400.270<.00136view →
KIRCDFSQuartileAll0.5400.656.00535view →
ESCAOSQuartileIII,IV0.3620.633.00922view →
THCAOSTertileIV0.5790.987<.00118view →
HNSCDFSQuartileIII,IV0.4560.299.02615view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

RNU6-725P–OV (OS)

Kaplan–Meier survival curve for RNU6-725P RNA-high vs -low samples in OV.

Open the OV breakdown →

Exploration