Across TCGA patient cohorts, RNU6-721P mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNU6-721P-associated genes across cancer lineages are ASNS, eEF2, and EGFR_pY1068. Each is linked with RNU6-721P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-721P-to-partner and partner-to-RNU6-721P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-721P→partner) and Y-score (partner→RNU6-721P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.425	+3.000	.019	.036	3	2
UCEC	eEF2 →	+0.643	+3.459	<.001	.005	3	1
UCEC	EGFR_pY1068 →	-0.333	-3.459	.008	.005	3	1
UCEC	ERK2 →	+0.297	+3.169	.002	.019	3	1
UCEC	ETS-1 →	+0.320	+2.321	.045	.035	3	1
UCEC	FOXO3a_pS318_S321 →	-0.202	-3.459	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

RNU6-721P survival (RNA) · tumor vs normal (RNA) · all RNU6-721P data types