RNU6-714P

Across TCGA patient cohorts, RNU6-714P mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible RNU6-714P-associated genes across cancer lineages are RNU6-208P, RPS3AP33, and BMS1P11. Each is linked with RNU6-714P in more than 1 cancer types. Because this analysis shows association rather than direction, both RNU6-714P-to-partner and partner-to-RNU6-714P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-208P grouped by RNU6-714P-low versus RNU6-714P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (RNU6-714P→partner) and Y-score (partner→RNU6-714P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-208P →	+0.549	+4.578	.007	.004	3	1
UCEC	RPS3AP33 →	+0.154	+5.109	<.001	.001	3	1
UCEC	BMS1P11 →	+0.118	+4.606	.009	.004	3	1
UCEC	RN7SL791P →	+0.219	+5.027	<.001	.004	3	1
UCEC	POU5F1P7 →	+0.084	+5.582	<.001	.002	3	1
UCEC	RNU6-1143P →	+0.676	+4.473	.007	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

RNU6-208P by RNU6-714P expression — UCEC

Explore this box plot interactively →