RNU6-705P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-705P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-705P data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher RNU6-705P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-705P expression acts as an unfavorable survival marker, although some lineages such as THYM and LAML show a favorable association.

DLBC, KICH, and LUAD are the cancer types where RNU6-705P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
DLBCDFSTertileAll0.1100.959<.00190view →
KICHOSTertileAll0.7920.988.00266view →
LUADDFSQuartileIV0.1320.687.00351view →
LIHCOSTertileAll0.3100.612.00139view →
COADOSTertileAll0.7400.882.00724view →
MESOOSTertileIV0.0770.592.01918view →
READDFSTertileIV0.3050.690.01812view →
THYMDFSMedianAll1.0000.712.0167view →
CHOLOSTertileIII,IV0.2900.855.0276view →
PRADOSTertileAll0.5950.932.0116view →
LAMLDFSTertileAll0.5690.317.0494view →
BRCAOSMedianIV0.7880.392.0243view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

Exploration