Across TCGA pan-cancer cohorts, RNU6-684P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU6-684P data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher RNU6-684P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-684P expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

ESCA, LAML, and UCS are the cancer types where RNU6-684P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	III,IV	0.133	0.582	<.001	36	view →
LAML	DFS	Tertile	All	0.214	0.587	.001	36	view →
UCS	DFS	Tertile	All	0.136	0.523	.034	18	view →
LGG	DFS	Tertile	All	0.893	0.820	.032	6	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: RNU6-684P tumor-vs-normal RNA expression · all RNU6-684P data types