RNU6-675P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-675P RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated RNU6-675P data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher RNU6-675P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-675P expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

UCEC, BLCA, and LUSC are the cancer types where RNU6-675P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSTertileAll0.2940.651.00260view →
BLCAOSTertileAll0.1110.720<.00154view →
LUSCDFSTertileII,III,IV0.1840.594.02145view →
PAADOSTertileAll0.1070.640<.00136view →
ESCAOSTertileAll0.1980.872.00336view →
LAMLDFSQuartileAll0.6060.292.00932view →
SKCMOSTertileIII,IV0.2490.705.00315view →
PCPGOSTertileAll0.8530.975.0469view →
Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

Exploration