RNU6-659P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-659P RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated RNU6-659P data layer.

The strongest signal is observed in testicular germ cell tumors (TGCT), where higher RNU6-659P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-659P expression acts as an unfavorable survival marker.

TGCT, LUSC, and LUAD are the cancer types where RNU6-659P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
TGCTOSTertileAll0.5080.991<.00190view →
LUSCDFSTertileAll0.3150.668<.00175view →
LUADOSTertileII,III,IV0.1090.750<.00154view →
BLCADFSTertileAll0.3920.635.00124view →
UCSDFSTertileAll0.1360.523.03418view →
BRCADFSTertileII,III,IV0.2450.530.00312view →
KIRCDFSTertileAll0.4000.657.0186view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

RNU6-659P–TGCT (OS)

Kaplan–Meier survival curve for RNU6-659P RNA-high vs -low samples in TGCT.

Open the TGCT breakdown →

Exploration