RNU6-658P

Across TCGA pan-cancer cohorts, RNU6-658P RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated RNU6-658P data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher RNU6-658P RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated RNU6-658P expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCS show a favorable association.

BRCA, LIHC, and UVM are the cancer types where RNU6-658P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	DFS	Median	III,IV	0.615	0.350	.001	44	view →
LIHC	DFS	Median	All	0.460	0.606	<.001	43	view →
UVM	DFS	Median	III,IV	0.304	0.706	<.001	42	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
COAD	DFS	Quartile	III,IV	0.171	0.577	.004	34	view →
THCA	OS	Quartile	III,IV	0.723	1.000	.020	24	view →
MESO	DFS	Tertile	All	0.290	0.464	.013	15	view →
LGG	DFS	Tertile	All	0.759	0.882	.006	14	view →
CESC	DFS	Quartile	All	0.728	0.854	.014	12	view →
DLBC	OS	Quartile	All	0.729	0.980	.012	11	view →
ESCA	DFS	Quartile	All	0.634	0.393	.013	9	view →
READ	OS	Tertile	IV	1.000	0.515	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

RNU6-658P–BRCA (DFS)

Open the BRCA breakdown →