RNU6-657P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-657P RNA is linked to patient survival in 5 of 34 cancer types, making it the most broadly survival-associated RNU6-657P data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher RNU6-657P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated RNU6-657P expression acts as an unfavorable survival marker.

KIRC, ESCA, and STAD are the cancer types where RNU6-657P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileII,III,IV0.1670.760<.00172view →
ESCAOSTertileIV0.0950.512.00836view →
STADDFSTertileIV0.1400.502.00524view →
OVDFSTertileIV0.1490.469.03118view →
SARCOSTertileAll0.1880.734<.00118view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration