RNU6-656P

Across TCGA pan-cancer cohorts, RNU6-656P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated RNU6-656P data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher RNU6-656P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-656P expression acts as an unfavorable survival marker, although some lineages such as STAD and LAML show a favorable association.

THCA, KIRP, and HNSC are the cancer types where RNU6-656P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Tertile	All	0.775	0.941	<.001	81	view →
KIRP	DFS	Tertile	II,III,IV	0.037	0.783	<.001	60	view →
HNSC	OS	Tertile	III,IV	0.189	0.748	<.001	36	view →
ESCA	DFS	Tertile	III,IV	0.228	0.472	.008	27	view →
BLCA	DFS	Tertile	III,IV	0.139	0.572	.026	18	view →
KIRC	DFS	Tertile	IV	0.127	0.630	.039	18	view →
SARC	DFS	Tertile	All	0.062	0.596	<.001	15	view →
STAD	OS	Tertile	III,IV	0.779	0.599	.032	15	view →
GBM	DFS	Tertile	All	0.071	0.288	.009	9	view →
LAML	DFS	Tertile	All	0.806	0.529	.047	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

RNU6-656P–THCA (OS)

Open the THCA breakdown →