RNU6-64P

Across TCGA pan-cancer cohorts, RNU6-64P RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated RNU6-64P data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher RNU6-64P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-64P expression acts as an unfavorable survival marker, although some lineages such as HNSC and LAML show a favorable association.

UVM, TGCT, and MESO are the cancer types where RNU6-64P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	All	0.104	0.858	<.001	99	view →
TGCT	DFS	Tertile	II,III,IV	0.015	0.919	<.001	54	view →
MESO	DFS	Tertile	III,IV	0.082	0.414	.007	54	view →
UCS	DFS	Tertile	All	0.154	0.537	.006	54	view →
OV	DFS	Tertile	All	0.295	0.544	.007	54	view →
KIRC	DFS	Tertile	IV	0.083	0.641	<.001	36	view →
COAD	DFS	Tertile	III,IV	0.035	0.698	<.001	27	view →
LGG	OS	Tertile	All	0.197	0.451	.008	24	view →
GBM	OS	Tertile	All	0.024	0.416	<.001	18	view →
BLCA	OS	Tertile	All	0.395	0.624	.041	18	view →
HNSC	DFS	Tertile	All	0.914	0.594	.019	12	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

RNU6-64P–UVM (OS)

Open the UVM breakdown →