RNU6-649P

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, RNU6-649P RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated RNU6-649P data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher RNU6-649P RNA is associated with worse overall survival. In most high-consensus cancer types, elevated RNU6-649P expression acts as an unfavorable survival marker.

BLCA, ESCA, and SKCM are the cancer types where RNU6-649P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
BLCAOSTertileAll0.1300.720<.001144view →
ESCADFSTertileIII,IV0.1230.462<.00181view →
SKCMOSTertileIII,IV0.2160.806<.00133view →
BRCADFSTertileII,III,IV0.7410.942.00812view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

Exploration